Protein Data Bank (PDB)

• The Protein Data Bank (PDB) : a repository for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids.

•  The data, typically obtained by X-ray crystallography or NMR spectroscopy and submitted by biologists andbiochemists from around the world.

• The PDB is overseen by an organization called the Worldwide Protein Data Bank, wwPDB.

Examples Of Protein:

LIPASE

NEPRILYSIN

HTPX

LONA

PROLYL

LEXA

Description of Protein:

LIPASE	The binding of Thermomyces lanuginosa lipase and its mutants [TLL(S146A), TLL(W89L), TLL(W117F, W221H, W260H)] to the mixed micelles of cis-parinaric acid/sodium taurodeoxycholate at pH 5.0 led to the quenching of the intrinsic tryptophan fluorescence emission (300-380 nm) and to a simultaneous increase in the cis-parinaric acid fluorescence emission (380-500 nm).
NEPRILYSIN	Neutral endopeptidase (NEP) is the major enzyme involved in the metabolic inactivation of a number of bioactive peptides including the enkephalins, substance P, endothelin, bradykinin and atrial natriuretic factor.
HTPX	is an enzyme that catalyzes the hydrolysis of a chemical bond. For example, an enzyme that catalyzed the following reaction is a hydrolase:
LONA	Lon ATP-dependent proteases are key components of the protein quality control systems of bacterial cells and eukaryotic organelles. Eubacterial Lon proteases contain an N-terminal domain, an ATPase domain, and a protease domain, all in one polypeptide chain.
PROLYL	The solution structure of the periplasmic cyclophilin type cis-trans peptidyl-prolyl isomerase from Escherichia coli (167 residues, MW > 18.200) has been determined using multidimensional heteronuclear NMR spectroscopy and distance geometry calculations.
LEXA	LexA repressor undergoes a self-cleavage reaction. In vivo, this reaction requires an activated form of RecA, but it occurs spontaneously in vitro at high pH.

LINKS:

• RSCB Protein Data Bank
• Wikipedia Protein Data Bank